Resistance to single-agent chemotherapy and its risk factors in low-risk gestational trophoblastic neoplasms
نویسندگان
چکیده
منابع مشابه
Efficacy of combination therapy of Methotrexate and Vitamin A in low risk gestational trophoblastic neoplasia treatment
Introduction: Methotrexate as a single agent chemotherapy in most women with low risk gestational trophoblastic neoplasia (GTN) has been associated with high treatment rate. Combination of methotrexate with Vitamin A due to reduced number of chemotherapy regime courses is one of the treatment options for patients with low-risk GTN. Therefore, this study was performed with aim to determine the e...
متن کاملEfficacy of combination therapy of Methotrexate and Vitamin A in low risk gestational trophoblastic neoplasia treatment
Introduction: Methotrexate as a single agent chemotherapy in most women with low risk gestational trophoblastic neoplasia (GTN) has been associated with high treatment rate. Combination of methotrexate with Vitamin A due to reduced number of chemotherapy regime courses is one of the treatment options for patients with low-risk GTN. Therefore, this study was performed with aim to determine the e...
متن کاملSingle-Agent Therapy for Low Risk Gestational Trophoblastic Neoplasia (LRGTN): A Preliminary Report on a Randomized Clinical Trial to Compare Pulse-Methotrexate versus Pulse-Dactinomycin
The efficacy of single-agent chemotherapy for patients with low risk gestational trophoblastic neoplasia (LRGTN) with methotrexate or dactinomycin is well established, but efforts continue to reduce the toxicity, the patients time and cost of treatment. In a randomized clinical trial, we evaluated and compared the efficacy, toxicity and cost effectiveness of pulse-methotrexate versus pulse-dact...
متن کاملPostmolar gestational trophoblastic neoplasia: beyond the traditional risk factors.
OBJECTIVE To investigate the slope of linear regression of postevacuation serum hCG as an independent risk factor for postmolar gestational trophoblastic neoplasia (GTN). DESIGN Multicenter retrospective cohort study. SETTING Academic referral health care centers. PATIENT(S) All subjects with confirmed hydatidiform mole and at least four measurements of β-hCG titer. INTERVENTION(S) None...
متن کاملPrevalence of Gestational Diabetes and Its Risk Factors in Meibod-Yazd 2013-2014
Introduction: Diabetes is the most common and important metabolic disorder in pregnancy period. This study aimed to determine the prevalence of gestational diabetes and its risk factors in Meibod County Materials and Methods: This cross-sectional study was carried out using registered data of diabetes screening program for all pregnant women living in Meibod town during the years 2013-2014. ...
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ژورنال
عنوان ژورنال: Journal of Obstetrics and Gynaecology Research
سال: 2014
ISSN: 1341-8076
DOI: 10.1111/jog.12613